Proteolipid protein cannot replace P0protein as the major structural protein of peripheral nervous system myelin
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چکیده
منابع مشابه
Proteolipid protein cannot replace P0 protein as the major structural protein of peripheral nervous system myelin.
The central nervous system (CNS) of terrestrial vertebrates underwent a prominent molecular change when proteolipid protein (PLP) replaced P0 protein as the most abundant protein of CNS myelin. However, PLP did not replace P0 in peripheral nervous system (PNS) myelin. To investigate the possible consequences of a PLP to P0 shift in PNS myelin, we engineered mice to express PLP instead of P0 in ...
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ژورنال
عنوان ژورنال: Glia
سال: 2014
ISSN: 0894-1491
DOI: 10.1002/glia.22733